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Recent Updates

Dates reflect substantive content updates recorded in article frontmatter.

  1. Anoscopy

    Direct examination of the anal canal and lowest rectum using a short illuminated instrument.

  2. Causes & Risk Factors

    How normal hemorrhoidal cushions become symptomatic and how bowel habit, pregnancy, aging, and other factors contribute.

  3. Conservative Treatment

    Fiber, fluids, bowel-habit changes, short-term symptom relief, and reassessment for hemorrhoids.

  4. Diagnosis & Examination

    History, inspection, digital rectal examination, anoscopy, colon evaluation, and differential diagnosis for hemorrhoids.

  5. Goligher Classification

    Four grades describing the degree and reducibility of internal hemorrhoid prolapse.

  6. Hemorrhoidal Artery Ligation

    Nonexcisional operation that ties arterial branches supplying internal hemorrhoids, sometimes with mucopexy.

  7. Hemorrhoidectomy

    Surgical excision of symptomatic internal, external, or combined hemorrhoidal tissue.

  8. Hemorrhoids

    A plain-English and clinical overview of hemorrhoids, symptoms, assessment, and treatment.

  9. Injection Sclerotherapy

    Office treatment that injects a sclerosant into selected internal hemorrhoidal tissue.

  10. Internal and External Hemorrhoids

    Hemorrhoidal tissue above and below the dentate line, with different symptom patterns and treatment considerations.

  11. Office Procedures

    Rubber band ligation, sclerotherapy, infrared coagulation, selection, recurrence, pain, and complications.

  12. Recovery & Prevention

    Pain, bowel movements, activity, expected bleeding, warning signs, recurrence, and follow-up after hemorrhoid treatment.

  13. Rectal Bleeding

    Blood passed from the anus, with causes ranging from minor anorectal conditions to serious bowel disease.

  14. Rubber Band Ligation

    Office treatment that places a small band around selected internal hemorrhoidal tissue.

  15. Stapled Hemorrhoidopexy

    Operation that lifts prolapsing internal hemorrhoidal tissue using a circular stapled mucosal resection.

  16. Surgical Treatment

    Excisional hemorrhoidectomy, stapled hemorrhoidopexy, hemorrhoidal artery ligation, indications, and tradeoffs.

  17. Symptoms & Grading

    Bleeding, prolapse, itching, discomfort, thrombosis, and Goligher grading in hemorrhoidal disease.

  18. Causes & Risk Factors

    What is known about immune biology, genetic susceptibility, and environmental associations in multiple sclerosis.

  19. Clinically Isolated Syndrome

    A first clinical episode compatible with inflammatory demyelination that may or may not meet criteria for multiple sclerosis.

  20. Diagnosis & MRI

    How clinical context, MRI, cerebrospinal fluid, optic nerve testing, and the McDonald criteria support an MS diagnosis.

  21. Disease Courses

    Relapsing-remitting, secondary progressive, and primary progressive patterns in multiple sclerosis.

  22. Disease-Modifying Therapy

    Long-term treatment intended to reduce new inflammatory activity and future injury in multiple sclerosis.

  23. Headache

    Head pain considered by pattern, associated symptoms, and clinical context.

  24. Living With Multiple Sclerosis

    Practical planning for fatigue, heat, activity, work, cognition, mental health, preventive care, and follow-up in MS.

  25. McDonald Criteria

    Specialist diagnostic criteria that organize clinical, imaging, cerebrospinal fluid, and optic nerve evidence for multiple sclerosis.

  26. MRI

    Magnetic resonance imaging of brain tissue and other structural findings.

  27. Multiple Sclerosis

    A plain-English and clinical overview of multiple sclerosis, diagnosis, disease courses, and treatment.

  28. Multiple Sclerosis Relapse

    A new episode of inflammatory neurologic dysfunction distinguished from pseudo-relapse, progression, and emergencies.

  29. Oligoclonal Bands

    Cerebrospinal fluid evidence of intrathecal immunoglobulin production used in selected neurologic evaluations.

  30. Optic Neuritis

    Inflammation of the optic nerve causing subacute visual loss, color desaturation, and sometimes pain with eye movement.

  31. Relapses & Recovery

    How clinicians distinguish an MS relapse from pseudo-relapse, progression, and other urgent neurologic conditions.

  32. Symptoms

    Common multiple sclerosis symptoms, localization patterns, and warning signs that need urgent assessment.

  33. Treatment

    Disease-modifying therapy, relapse treatment, rehabilitation, symptom management, and monitoring for multiple sclerosis.

  34. Arterial Spin Labeling MRI

    A noninvasive MRI perfusion method that labels arterial blood magnetically.

  35. Causes & Genetics

    What is known about the causes, familial patterns, RNF213, and associated conditions in moyamoya.

  36. Cerebral Hyperperfusion Syndrome

    A postoperative state in which regional blood flow rises beyond the tissue’s ability to regulate it.

  37. Cerebrovascular Reserve

    The capacity of cerebral vessels to increase blood flow when demand rises or pressure changes.

  38. Combined Revascularization

    An operation that combines direct bypass with one or more indirect revascularization techniques.

  39. Diagnosis & Imaging

    How MRI, MRA, angiography, perfusion testing, and diagnostic criteria are used in moyamoya.

  40. Digital Subtraction Angiography

    An invasive catheter angiographic technique that produces high-detail images of blood vessels and blood flow.

  41. Direct Revascularization

    Microsurgical bypass that immediately connects an extracranial donor artery to a cerebral recipient artery.

  42. EDAS

    Encephaloduroarteriosynangiosis, an indirect revascularization procedure using a scalp artery.

  43. EMS and EDAMS

    Indirect revascularization techniques using temporalis muscle, with or without a scalp artery and dura.

  44. Indirect Revascularization

    Procedures that place vascularized tissue near the brain so new collateral vessels can develop.

  45. Intracranial Hemorrhage

    Bleeding within the skull, including the brain tissue, ventricles, or other intracranial spaces.

  46. Ischemic Stroke

    Brain injury caused by inadequate blood flow and oxygen.

  47. Living With Moyamoya

    Practical topics to discuss with a care team when living with moyamoya disease.

  48. Moyamoya Disease

    A plain-English and clinical overview of moyamoya disease, diagnosis, risks, and treatment.

  49. Moyamoya Syndrome

    Moyamoya-pattern vasculopathy associated with another medical condition or exposure.

  50. MRA

    Noninvasive magnetic resonance angiography of cerebral arteries.

  51. Multiple Burr Holes

    An indirect revascularization technique using several small skull openings.

  52. PET

    Positron emission tomography for quantitative cerebral hemodynamic assessment.

  53. Pial Synangiosis

    An indirect technique that places a scalp artery directly against the pial surface.

  54. Puff-of-Smoke Appearance

    The angiographic collateral appearance that gave moyamoya disease its name.

  55. Recovery & Follow-up

    What follow-up commonly monitors before and after moyamoya revascularization surgery.

  56. RNF213

    A susceptibility gene associated with moyamoya disease in some populations.

  57. SPECT

    Nuclear medicine perfusion imaging used to assess cerebral blood flow and reserve.

  58. STA–MCA Bypass

    A direct bypass connecting the superficial temporal artery to a middle cerebral artery branch.

  59. Surgical Procedures

    Direct, indirect, and combined cerebral revascularization procedures used for moyamoya.

  60. Suzuki Staging

    An angiographic description of how moyamoya collateral patterns evolve.

  61. Symptoms

    Symptoms and emergency warning signs associated with moyamoya disease in children and adults.

  62. Transient Ischemic Attack

    Temporary focal neurologic symptoms caused by inadequate blood flow without established infarction.

  63. Treatment

    An overview of medical management, surgical decision-making, and multidisciplinary care for moyamoya.