Cerebral Hyperperfusion Syndrome

In brief: Cerebral hyperperfusion syndrome is a potential complication after revascularization in which regional blood flow increases more than impaired tissue can initially regulate.

Possible features include headache, seizures, transient focal symptoms, edema, or hemorrhage. Similar symptoms can also result from ischemia, and the distinction requires clinical assessment and imaging rather than assumption.

Use in moyamoya disease

Postoperative protocols may use blood-pressure management and perfusion monitoring while avoiding ischemia in other vulnerable territories. Japanese guidance emphasizes balancing these competing risks. [1]

Clinical detail

Definitions and measured thresholds differ among studies. A high perfusion value without symptoms is not automatically equivalent to the clinical syndrome.